Khairunnisa is a graduate of University of Tasmania with M.Mus. A recipient of Jessie Wakefield-Luckman Prize for Voice, University of Tasmania and Lestrai Grant UiTM (Indie Music in Malaysia), Khairunnisa has appeared in live telecast radio performance for 3MBS radio stations in Melbourne, Australia as well as in various solo recitals and chamber concerts locally such as A Celebration of Voice (Muzium Negara, Kuala Lumpur), The Eximious Concert (Istana Budaya, Kuala Lumpur), Opera Puteri Saadong (KLPAC Kuala Lumpur and many more. In 2017, she had her first performance in London for the British Malaysia Society 60th Anniversary of Malaysian Independence Concert. Recently, in May 2019, she was invited to perform alongside with Tun Dr Siti Hasmah binti Haji Mohamad Ali for Kasih Perak Charity Gala Dinner (MAPS, Ipoh).
Khairunnisa has also given lectures and workshops at various higher learning institutions, locally including UNIMAP and Petrosains and has served as jury member for solo singing and choral competitions at regional, state and national levels. She is currently working as a Diploma Coordinator at the Faculty of Music, UiTM Shah Alam. She performs regularly with VerSeS and is a strong supporter of indie classical music, Malaysian folk tunes and outreach programmes such as The Singing Balcony.